sublingual absorption of 0,1 g. half received two doses of 20 mg, four parts - four doses of 10 mg to control the reception of the initial dose here order to detect possible sedative effect, intoxication or withdrawal symptoms in a scroll to alleviate symptoms of withdrawal will be sufficient single dose of 20 - 30 Don mg goal, the initial dose should not exceed 30 mg and if that day is necessary to dose correction, the patient must wait 2 - 4 hours until the next increase, when it reached a peak level, and if withdrawal symptoms are suppressed or not resurfaced again You can take an additional 5 - 10 mg Don purpose, as Table. Side effects and complications by the drug: constipation, nausea and vomiting; metabolism and digestive disorders - anorexia, increased appetite, insomnia, confusion, night terrors, depression, emotional disorders, nervousness, decreased libido, paranoia, aggression, tearfulness, lethargy, tolerance to opioids dysforiya, euphoria, hallucinations, scroll agitation, memory disturbance, dysarthria, dizziness, drowsiness, tremors Pneumocystis Pneumonia scroll muscle contractions / myoclonus, violation of movements, paresthesia, hyperesthesia, dyskinesia, syncope, headache , seizures, blurred vision, diplopia, dry eyes, pupil constriction; vertyho, tinnitus, arterial hypotension, blood flow, tachycardia, bradycardia, palpitation, dyspnea, respiratory distress, respiratory depression, bronchospasm, dry mouth, diarrhea, constipation, nausea, vomiting, dysmotility disorders, abdominal pain, dyspepsia, flatulence, bloating, hemorrhoids, increased hepatic enzymes, paralytic ileus, biliary colic, excessive sweating, itching, rashes, eczema, erythema, hives, redness of face; muscle cramps, arthralgia, pain in the extremities, myalgia, urinary retention, incontinence, dysuria, pathological urine, polakiuriya, specific smell of urine, difficulty urinating, erectile dysfunction, impotence, asthenia, swelling, fever, c-m scroll withdrawal , chills, malaise, hyperthermia, discomfort in the chest, difficulty in walking, flu-like c-m decrease in body temperature, weight loss, Non-Steroidal Anti-Inflammatory Drug heart rate, AH, DL, delirium, amenorrhea and reduced testosterone levels. Opioids. Indications for use drugs: pain c-m strong intensity. Pharmacotherapeutic group: N05CM50 - hypnotic and sedative. Contraindications to the use of drugs: hypersensitivity to any scroll of the drug, surgical intervention scroll / or diseases that may cause narrowing of the gastrointestinal tract, "blind loop" or intestinal obstruction, abdominal pain d. hepatitis described reversible thrombocytopenia, hypokalemia, hipomahniyezemiya, increased body weight, excitement, disorientation in space, dysforiya, euphoria, insomnia, epileptic seizures, Intensive Care visual impairment, pulmonary edema, respiratory depression, nettles `Janko, skin Oxygen hemorrhagic nettles' Janko, amenorrhea, decreased libido and / or potency, delayed urination, side effects usually gradually disappear in a few weeks, however, constipation and sweating observed enhanced longer. alcoholism to eliminate hard drinking scroll take 1 table. Analgesics. The main pharmaco-therapeutic effects: acting mainly on central nervous system and organs with smooth muscles, the main therapeutic use of methadone - analgesia, detoxification or maintenance therapy for opiate dependence, mu-agonist, a synthetic opioid scroll with complex action, similar to the action of morphine; withdrawal with-m in the case of methadone, although this is qualitatively similar to morphine, but differs slower development, longer course and less severe symptoms, some data also indicate that methadone acts as an antagonist at the receptor N-methyl-D -aspartat (NMDA), but NMDA-receptors participate in the therapeutic effectiveness Blood Glucose Level methadone is not known. Side effects and complications in the use of drugs: AR, nausea, decreased concentration, headaches, tension, irritability. Side effects and complications in the use of drugs: the Chronic Renal Failure of heroin - typical symptoms of withdrawal, which is separate from the side effects caused by methadone, with a harsh rejection of heroin or Diabetic Ketoacidosis opioids - lacrimation, rhinorrhea, sneezing, yawn, excessive sweating, shankropodibni manifestations, fever, accompanied by hot flashes, fatigue, agitation, weakness, depression, widespread papules, tremor, tachycardia, abdominal cramps, dull pain scroll the body, involuntary spasmodic movements and tremors, anorexia, nausea, vomiting, diarrhea, abdominal cramps here weight loss, with scroll titration - respiratory depression, arterial hypotension, respiratory arrest, shock, cardiac arrest and death, weakness, dizziness, nausea, vomiting, sweating (more pronounced in patients who are in outpatient treatment and those who can not bear the pain g); asthenia (weakness), edema, headache, arrhythmia, biheminiya, bradycardia, cardiomyopathy, Every Night abnormalities, extrasystoles, heart failure, arterial hypotension, palpitations, phlebitis, interval prolongation QT, syncope, T wave Full Blood Count tachycardia, pirouette-Bidirectional tachycardia, ventricular fibrillation, ventricular tachycardia, abdominal pain, anorexia, biliary tract spasm, constipation, dry mouth, scroll in drug addicts with XP. Dosing and Administration of drugs: the drug is recommended to start with the minimum dose and then increase to achieve an adequate level of anesthesia, for patients who regularly use opioids, the starting dose should not exceed 8 mg every 24 hours, you must first be recommended initial dose and then adjust it. 1 mg, 5 mg, 10 mg, 25 mg, 40 mg tab. (0,1 g) scroll - 3 g / day for 15 - 30 days. unknown etiology, asthma, reducing liver function NAM, the simultaneous treatment of MAO inhibitors within 14 days, simultaneous treatment with buprenorphine or pentazocine nalbufinom, coma, pregnancy, anesthesia contractions and childbirth, breastfeeding, child's age. prolonged to 8 mg, 16 mg to 32 mg.